Publications
| Authors | Publication | Title | DOI |
| Houlahan, K. E., Mangiante, L., Sotomayor-Vivas, C., Adimoelja, A., Park, S., Khan, A., Pribus, S. J., Ma, Z., Caswell-Jin, J. L., & Curtis, C. | Nature | Complex rearrangements fuel ER+ and HER2+ breast tumours | https://doi.org/10.1038/s41586-024-08377-x |
| Baracuhy, E. M., Cormier, O., Davola, M. E., Collins, S., & Mossman, K. | Molecular Therapy Oncology | Virus replication is not required for oncolytic bovine herpesvirus-1 immunotherapy | http://doi.org/10.1016/j.omton.2024.200906 |
| Mikolajewicz, N., Tatari, N., Wei, J., Savage, N., Granda Farias, A., Dimitrov, V., Chen, D., Zador, Z., Dasgupta, K., Aguilera-Uribe, M., Xiao, Y. X., Lee, S. Y., Mero, P., McKenna, D., Venugopal, C., Brown, K. R., Han, H., Singh, S., & Moffat, J. | Acta Neuropathologica | Functional profiling of murine glioma models highlights targetable immune evasion phenotypes | https://doi.org/10.1007/s00401-024-02831-w |
| Radford, M., Garcia-Horton, A., Badami, R., Jin, E., Usmani, N., Grafodatskaya, D., McCready, E., Khalaf, D., Walker, I., Leber, B., Lepic, K., Pond, G., & Berg, T. | Transplantation and Cellular Therapy | Early mixed donor chimerism is a strong negative prognostic indicator in allogeneic stem cell transplant for AML and MDS | http://doi.org/10.1016/j.jtct.2024.11.006 |
| Portillo, A. L., Rojas, E. A., Mehboob, M., Moinuddin, A., Balint, E., Feng, E., Silvestri, C., Vahedi, F., Ritchie, T. M., Mansour, A. J., Bramson, J. L., & Ashkar, A. A. | Journal of Leukocyte Biology | CD56 does not contribute to the anti-tumor, tissue homing, and glycolytic capacity of human NK cells | https://doi.org/10.1093/jleuko/qiae227 |
| Deng, L., Walsh, S. R., Nguyen, A., Inkol, J. M., Westerveld, M. J., Chen, L., El-Sayes, N., Mossman, K. L., Workenhe, S. T., & Wan, Y | Cancer Immunology Research | Level of expression of MHCI-presented neoepitopes influences tumor rejection by neoantigen-specific CD8+ T cells | https://doi.org/10.1158/2326-6066.CIR-23-0639 |
| Kang, A., Ye, G., Afkhami, S., Aleithan, F., Singh, K., Dvorkin-Gheva, A., Berg, T., Miller, M. S., Jeyanathan, M., & Xing, Z | Cell Reports | LPS-induced lung tissue-resident trained innate immunity provides differential protection against pneumococci and SARS-CoV-2 | https://doi.org/10.1016/j.celrep.2024.114849 |
| Kieliszek, A. M., Mobilio, D., Bassey-Archibong, B. I., Johnson, J. W., Piotrowski, M. L., de Araujo, E. D., Sedighi, A., Aghaei, N., Escudero, L., Ang, P., Gwynne, W. D., Zhang, C., Quaile, A., McKenna, D., Subapanditha, M., Tokar, T., Vaseem Shaikh, M., Zhai, K., Chafe, S. C., Gunning, P. T., … Singh, S. K. | Cell Reports Medicine | De novo GTP synthesis is a metabolic vulnerability for the interception of brain metastases | https://doi.org/10.1016/j.xcrm.2024.101755 |
| Iwashkiw, J. A., Mohamud, A. O., Kazhdan, N., Ameen, A., Beecher, J. E., Filipe, C. D. M., & Lichty, B. D. | Scientific Reports | Improved thermal stabilization of VSV-vector with enhanced vacuum drying in pullulan and trehalose-based films | http://doi.org/10.1038/s41598-024-69003-4 |
| Wu, Q., Rafatian, N., Wagner, K. T., Blamer, J., Smith, J., Okhovatian, S., Aggarwal, P., Wang, E. Y., Banerjee, A., Zhao, Y., Nash, T. R., Lu, R. X. Z., Portillo-Esquivel, L. E., Li, C. Y., Kuzmanov, U., Mandla, S., Virlee, E., Landau, S., Lai, B. F., Gramolini, A. O., Mossman, K | Proceedings of the National Academy of Sciences of the United States of America | SARS-CoV-2 pathogenesis in an angiotensin II–induced heart-on-a-chip disease model and extracellular vesicle screening | https://doi.org/10.1073/pnas.2403581121 |
| Wong, A., Duong, A., Wilson, G., Yeung, J., MacParland, S., Han, H., Cypel, M., Keshavjee, S., & Liu, M. | American Journal of Transplantation, Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons | Ischemia-reperfusion responses in human lung transplants at the single-cell resolution | https://doi.org/10.1016/j.ajt.2024.08.019 |
| Best, A. J., Braunschweig, U., Wu, M., Farhangmehr, S., Pasculescu, A., Lim, J. J., Comsa, L. C., Jen, M., Wang, J., Datti, A., Wrana, J. L., Cordes, S. P., Al-Awar, R., Han, H., & Blencowe, B. J. | Nature Communications | High-throughput sensitive screening of small molecule modulators of microexon alternative splicing using dual Nano and Firefly luciferase reporters | http://doi.org/10.1038/s41467-024-50399-6 |
| Krygier, K., Wijetunge, A. N., Srayeddin, A., Mccann, H., & Rullo, A. F. | ACS Chemical Biology | Leveraging Covalency to Stabilize Ternary Complex Formation For Cell–Cell “Induced Proximity” | https://doi.org/10.1021/acschembio.4c00286 |
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Chokshi, C. R., Shaikh, M. V., Brakel, B., Rossotti, M. A., Tieu, D., Maich, W., Anand, A., Chafe, S. C., Zhai, K., Suk, Y., Kieliszek, A. M., Miletic, P., Mikolajewicz, N., Chen, D., McNicol, J. D., Chan, K., Tong, A. H. Y., Kuhlmann, L., Liu, L., Alizada, Z., … Singh, SK
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Nature Medicine | Targeting axonal guidance dependencies in glioblastoma with ROBO1 CAR T cells | https://doi.org/10.1038/s41591-024-03138-9 |
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Serniuck N, Kapcan E, Moogk D, Moore A, Lake B, Denisova G, Hammill JA, Bramson JL, Rullo AF
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Molecular Therapy Oncology | Electrophilic proximity-inducing synthetic adapters enhance universal T cell function by covalently enforcing immune receptor signaling. | http://doi.org/10.1016/j.omton.2024.200842 |
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Budylowski, P., Chau, S. L. L., Banerjee, A., Guvenc, F., Samson, R., Hu, Q., Fiddes, L., Seifried, L., Chao, G., Buchholz, M., Estacio, A., Cheatley, P. L., Pavenski, K., Patriquin, C. J., Liu, Y., Sheikh-Mohamed, S., Crasta, K., Yue, F., Pasic, M. D., Mossman, K., … Ostrowski, M
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Journal of Immunology | A Significant Contribution of the Classical Pathway of Complement in SARS-CoV-2 Neutralization of Convalescent and Vaccinee Sera | https://doi.org/10.4049/jimmunol.2300320 |
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Wyszatko, K., Janzen, N., Silva, L. R., Kwon, L., Komal, T., Ventura, M., Venugopal, C., Singh, S. K., Valliant, J. F., & Sadeghi, S.
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EJNMMI research | 89Zr-labeled ImmunoPET targeting the cancer stem cell antigen CD133 using fully-human antibody constructs | https://doi.org/10.1186/s13550-024-01091-9 |
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Sharma, H., Mossman, K., Austin, R. C
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European Journal of Clinical Investigation | Fatal attractions that trigger inflammation and drive atherosclerotic disease | http://doi.org/10.1111/eci.14169 |
| Budylowski, P., Chau, S. L. L., Banerjee, A., Guvenc, F., Samson, R., Hu, Q., Fiddes, L., Seifried, L., Chao, G., Buchholz, M., Estacio, A., Cheatley, P. L., Pavenski, K., Patriquin, C. J., Liu, Y., Sheikh-Mohamed, S., Crasta, K., Yue, F., Pasic, M. D., Mossman, K., … Ostrowski, M. | Journal of Immunology | A Significant Contribution of the Classical Pathway of Complement in SARS-CoV-2 Neutralization of Convalescent and Vaccinee Sera | https://doi.org/10.4049/jimmunol.2300320 |
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Moinuddin A, Poznanski S, Portillo AL, Monteiro JK, Ashkar AA
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Immunological Review | Metabolic adaptations determine whether NK cells fail or thrive within the tumor microenvironment | http://doi.org/10.1111/imr.13316 |
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Singh, A., Lofts, A., Krishnan, R., Campea, M., Chen, L., Wan, Y., & Hoare, T
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Nanoscale Advances | The effect of comb length on the in vitro and in vivo properties of self-assembled poly(oligoethylene glycol methacrylate)-based block copolymer nanoparticles. | http://doi.org/10.1039/d3na01156a |
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Inkol, J. M., Westerveld, M. J., Verburg, S. G., Walsh, S. R., Morrison, J., Mossman, K. L., Worfolk, S. M., Kallio, K. L., Phippen, N. J., Burchett, R., Wan, Y., Bramson, J., & Workenhe, S. T
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Journal for ImmunoTherapy of Cancer | Pyroptosis activates conventional type I dendritic cells to mediate the priming of highly functional anticancer T cells | http://doi.org/10.1136/jitc-2023-006781 |
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Hollands, C. G., Boyd, A. L., Zhao, X., Reid, J. C., Henly, C., ElRafie, A., Boylan, D., Broder, E., Kalau, O., Johnson, P., Mark, A., McNicol, J., Xenocostas, A., Berg, T., Foley, R., Trus, M., Leber, B., Garcia-Horton, A., Campbell, C., & Bhatia, M
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Cell Reports Medicine | Identification of cells of leukemic stem cell origin with non-canonical regenerative properties. | http://doi.org/10.1016/j.xcrm.2024.101485. |
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Balint E, Giles E, Feng E, Ritchie TM, Vahedi F, Ashkar AA
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Nature Communications | Bystander activated CD8+ T cells mediate neuropathology during viral infection via antigen-independent cytotoxicity. | https://doi.org/10.1038/s41467-023-44667-0 |
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Nguyen A, Brown D, Krishnan R, Bastin D, Deng L, Chen L, Salem O, Walsh SR, Bramson JL, Wan Y.
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Clinical Cancer Research | HDACi-dependent Microenvironmental Normalization Overcomes Tumor Burden-induced T-cell Exhaustion. | http://doi.org/10.1158/1078-0432.ccr-22-2181 |
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Lake B, Rullo A
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ACS Central Science | Offsetting Low-Affinity Carbohydrate Binding with Covalency to Engage Sugar-Specific Proteins for Tumor-Immune Proximity Induction | https://doi.org/10.1021/acscentsci.3c01052 |
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Kieliszek AM, Mobilio D, Upreti D, Bloemberg D, Escudero L, Kwiecien JM, Alizada Z, Zhai K, Ang P, Chafe SC, Vora P, Venugopal C, Singh SK
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Clinical Cancer Research | Intratumoral Delivery of Chimeric Antigen Receptor-T Cells Targeting CD133 Effectively Treats Brain Metastases | https://doi.org/10.1158/1078-0432.ccr-23-1735 |
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Amr Ali, Bassem Mekhaeil, Olga-Demetra Biziotis, Evangelia E. Tsakiridis, Elham Ahmadi, Jianhan Wu, Simon Wang, Kanwaldeep Singh, Gabe Menjolian, Thomas Farrell, Aruz Mesci, Stanley Liu, Tobias Berg, Jonathan L. Bramson, Gregory R. Steinberg & Theodoros Tsakiridis
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Communications Biology | The SGLT2 inhibitor canagliflozin suppresses growth and enhances prostate cancer response to radiotherapy | https://www.nature.com/articles/s42003-023-05289-w |
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Biziotis OD, Tsakiridis EE, Ali A, Ahmadi E, Wu J, Wang S, Mekhaeil B, Singh K, Menjolian G, Farrell T, Abdulkarim B, Sur RK, Mesci A, Ellis P, Berg T, Bramson JL, Muti P, Steinberg GR, Tsakiridis T.
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Molecular Oncology | Canagliflozin mediates tumor suppression alone and in combination with radiotherapy in non-small cell lung cancer (NSCLC) through inhibition of HIF-1? | https://doi.org/10.1002/1878-0261.13508 |
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Bakhshinyan D, Suk Y, Kuhlman L, Adile AA, Ignatchenko V, Custers S, Gwynne WD, Mackling A, Venugopal C, Kislinger T, Singh SK
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Acta Neuropathologica Communications | Dynamic profiling of medulloblastoma surfaceome | https://doi.org/10.1186/s40478-023-01609-7 |
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Adile AA, Bakhshinyan D, Suk Y, Uehling D, Saini M, Aman A, Magolan J, Subapanditha MK, McKenna D, Chokshi C, Savage N, Kameda-Smith MM, Venugopal C, Singh SK
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Journal of Neuro-Oncology | An effective kinase inhibition strategy for metastatic recurrent childhood medulloblastoma. | https://doi.org/10.1007/s11060-023-04372-w |
| Bezverbnaya, K., Hammill, J.A., Cummings, D., Bojovic, B., Groisman, B., Baker, C.L., Aarts, C.A., Helsen, C.W., and Bramson, J.L. | Cytotherapy |
Development of a fully humanized BCMA-specific T cell antigen coupler (TAC) receptor | https://doi.org/10.1016/j.jcyt.2023.01.002 |
| Hartung E, Singh K, Berg T | Frontiers in Oncology | LSD1 inhibition modulates transcription factor networks in myeloid malignancies | https://doi.org/10.3389/fonc.2023.1149754 |
| Lv J, Zhou Y, Zhou N, Wang Z, Chen J, Chen H, Wang D, Zhou L, Wei K, Zhang H, Tang K, Ma J, Liu Y, Wan Y, Zhang Y, Zhang H, Huang B. | Science Translational Medicine | Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells | https://doi.org/10.1126/scitranslmed.abq6024 |
| Davola ME, Cormier O, Vito A, El-Sayes N, Collins S, Salem O, Revill S, Ask K, Wan Y, Mossman K. | Cancers |
Oncolytic BHV-1 Is Sufficient to Induce Immunogenic Cell Death and Synergizes with Low-Dose Chemotherapy to Dampen Immunosuppressive T Regulatory Cells | https://doi.org/10.3390/cancers15041295 |
| Adan H, Guy S, Arulanandam R, Geletu M, Daniel J, Raptis L | Cancer Gene Therapy |
Activated Src requires Cadherin-11, Rac, and gp130 for Stat3 activation and survival of mouse Balb/c3T3 fibroblasts | https://doi.org/10.1038/s41417-022-00462-5 |
| Seyfrid M, Maich WT, Shaikh VM, Tatari N, Upreti D, Piyasena D, Subapanditha M, Savage N, McKenna D, Mikolajewicz N, Han H, Chokshi C, Kuhlmann L, Khoo A, Salim SK, Archibong-Bassey B, Gwynne W, Brown K, Murtaza N, Bakhshinyan D, Vora P, Venugopal C, Moffat J, Kislinger T, Singh S | Journal for ImmunoTherapy of Cancer | CD70 as an actionable immunotherapeutic target in recurrent glioblastoma and its microenvironment | https://doi.org/10.1136/jitc-2021-003289 |
| Bassey-Archibong B, Chokshi C, Aghaei N, Kieliszek A, Tatari N, McKenna D, Singh M, Subapanditha M, Parmar A, Mobilio D, Savage N, Lam F, Tokar T, Provias J, Lu Y, Chafe S, Swanton C, Hynds R, Venugopal C, and Singh S | PNAS |
An HLA-G/SPAG9/STAT3 axis promotes brain metastases | https://doi.org/10.1073/pnas.2205247120 |
| Kapcan E, Rullo A | Cell Reports Physical Science |
A covalent opsonization approach to enhance synthetic immunity against viral escape variants | https://doi.org/10.1016/j.xcrp.2023.101258 |
| Lake BPM, Wylie RG, Barinka C, Rullo A | Angewandte Chemie | Tunable Synthetic Multivalent Platform for Immune Recruitment to Lower Antigen Expressing Cancers | https://doi.org/10.1002/anie.202214659 |
| Nguyen A, Ho L, Hogg R, Chen L, Walsh SR, Wan Y | The Journal of Clinical Investigation | HDACi promotes inflammatory remodeling of the tumor microenvironment to enhance epitope spreading and antitumor immunity | https://doi.org/10.1172/jci159283 |
| Kameda-Smith MM, Zhu H, Luo EC, Suk Y, Xella A, Yee B, Chokshi C, Xing S, Tan F, Fox RG, Adile AA, Bakhshinyan D, Brown K, Gwynne WD, Subapanditha M, Miletic P, Picard D, Burns I, Moffat J, Paruch K, Fleming A, Hope K, Provias JP, Remke M, Lu Y, Reya T, Venugopal C, Reimand J, Wechsler-Reya RJ, Yeo GW, Singh SK. | Nature Communications | Characterization of an RNA binding protein interactome reveals a context-specific post-transcriptional landscape of MYC-amplified medulloblastoma | https://doi.org/10.1038/s41467-022-35118-3 |
| William D. Gwynne, Yujin Suk, Stefan Custers, Nicholas Mikolajewicz, Jeremy K. Chan, Zsolt Zador, Shawn C. Chafe, Kui Zhai, Laura Escudero, Cunjie Zhang, Olga Zaslaver, Chirayu Chokshi, Muhammad Vaseem Shaikh, David Bakhshinyan, Ian Burns, Iqra Chaudhry, Omri Nachmani, Daniel Mobilio, William T. Maich, Patricia Mero, Kevin R. Brown, Andrew T. Quaile, Chitra Venugopal, Jason Moffat, J. Rafael Montenegro-Burke, Sheila K. Singh | Cancer Cell | Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma | https://doi.org/10.1016/j.ccell.2022.10.009 |
| Lessey LR, Robinson SC, Chaudhary R, Daniel JM. | Frontiers in Cell and Developmental Biology | Adherens junction proteins on the move-From the membrane to the nucleus in intestinal diseases | https://doi.org/10.3389/fcell.2022.998373 |
| Nazanin Tatari, Shahbaz Khan, Julie Livingstone, Kui Zhai, Dillon Mckenna, Vladimir Ignatchenko, Chirayu Chokshi, William D Gwynne, Manoj Singh, Spencer Revill, Nicholas Mikolajewicz, Chenghao Zhu, Jennifer Chan, Cynthia Hawkins, Jian-Qiang Lu, John P Provias , Kjetil Ask, Sorana Morrissy, Samuel Brown, Tobias Weiss, Michael Weller, Hong Han, Jeffrey N Greenspoon, Jason Moffat, Chitra Venugopal, Paul C Boutros, Sheila K Singh, Thomas Kislinger | Acta Neuropathologica | The proteomic landscape of glioblastoma recurrence reveals novel and targetable immunoregulatory drivers | https://doi.org/10.1007/s00401-022-02506-4 |
| Jessica A. Breznik, Angela Huynh, Ali Zhang, Lucas Bilaver, Hina Bhakta, Hannah D. Stacey, Jann C. Ang, Jonathan L. Bramson, Ishac Nazy, Matthew S. Miller, Judah Denburg, Andrew P. Costa and Dawn M. E. Bowdish | Journal of Immunology | Cytomegalovirus Seropositivity in Older Adults Changes the T Cell Repertoire but Does Not Prevent Antibody or Cellular Responses to SARS-CoV-2 Vaccination | https://doi.org/10.4049/jimmunol.2200369 |
| Qazi MA, Salim SK, Brown KR, Mikolajewicz N, Savage N, Han H, Subapanditha MK, Bakhshinyan D, Nixon A, Vora P, Desmond K, Chokshi C, Singh M, Khoo A, Macklin A, Khan S, Tatari N, Winegarden N, Richards L, Pugh T, Bock N, Mansouri A, Venugopal C, Kislinger T, Goyal S, Moffat J, Singh SK | Cell Reports | Characterization of the minimal residual disease state reveals distinct evolutionary trajectories of human glioblastoma | https://doi.org/10.1016/j.celrep.2022.111420 |
| Yujin Suk, Agata Kieliszek, Daniel Mobilio, Chitra Venugopal, Sheila K Singh | STAR Protocols | Derivation and culturing of neural stem cells from human embryonic brain tissue | https://doi.org/10.1016/j.xpro.2022.101628 |
| Han H, Best AJ, Braunschweig U, Mikolajewicz N, Li JD, Roth J, Chowdhury F, Mantica F, Nabeel-Shah S, Parada G, Brown KR, O’Hanlon D, Wei J, Yao Y, Zid AA, Comsa LC, Jen M, Wang J, Datti A, Gonatopoulos-Pournatzis T, Weatheritt RJ, Greenblatt JF, Wrana JL, Irimia M, Gingras AC, Moffat J, Blencowe BJ | Molecular Cell | Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis. | https://doi.org/10.1016/j.molcel.2022.06.036 |
| Adan H, Daniel J, Raptis L | Cells | Roads to Stat3 Paved with Cadherins | https://doi.org/10.3390/cells11162537 |
| Kleer M, Mulloy RP, Robinson CA, Evseev D, Bui-Marinos MP, Castle EL, Banerjee A, Mubareka S, Mossman K, Corcoran JA | PLoS Pathogens | Human coronaviruses disassemble processing bodies | https://doi.org/10.1371/journal.ppat.1010724 |
| Kaiyun Yang, Yosef Ellenbogen, Amanda Martyniuk, Michel Sourour, Radwan Takroni, Mohamed Somji, Emily Gardiner, Katrina Hui, Devang Odedra, Ramiro Larrazabal, Almunder Algird, Edward Kachur, Kesava Reddy, Naresh Murty, Forough Farrokhyar, Sheila K Singh | Neuro-Oncology Advances | Reoperation in adult patients with recurrent glioblastoma: A matched cohort analysis | https://doi.org/10.1093/noajnl/vdac115 |
| Lindsay A.Broadfield, Amna Saigal, Jake C.Szamosi, Joanne A. Hammill, Ksenia Bezverbnaya, Dongdong Wang Jaya Gautam, Evangelia E.Tsakiridis, Fiorella Di Pastena, Jamie McNicol, Jianhan Wu, Saad Syed, James S.V. Lally, Amogelang R. Raphenya, Marie-Jose Blouin, Michael Pollak, Andrea Sacconi, Giovanni Blandino, Andrew G.McArthur, Jonathan D.Schertzer, Michael G.Surette, Stephen M.Collins, Jonathan L. Bramson, Paola Muti, Theodoros Tsakiridis, Gregory R. Steinberg | Molecular Metabolism | Metformin-induced reductions in tumor growth involves modulation of the gut microbiome | https://doi.org/10.1016/j.molmet.2022.101498 |
| Yu Yan, Ram Upadhyaya, Vivian Weixuan Zhang, Tobias Berg | Experimental Hematology | Epigenetic maintenance strategies after allogeneic stem cell transplantation in acute myeloid leukemia | https://doi.org/10.1016/j.exphem.2022.03.003 |
| Harrison McCann, Benjamin Lake, Maria Davola, Karen Mossman, Anthony F. Rullo | ACS Chemical Biology | Covalent Immune Proximity-Induction Strategy Using SuFEx-Engineered Bifunctional Viral Peptides | https://doi.org/10.1021/acschembio.2c00233 |
| Lee AJ, Feng E, Chew MV, Balint E, Poznanski SM, Giles E, Zhang A, Marzok A, Revill SD, Vahedi F, Dubey A, Ayaub E, Jimenez-Saiz R, McGrath JJC, Ritchie TM, Jordana M, Jonigk DD, Ackermann M, Ask K, Miller M, Richards CD, Ashkar AA | PLoS Pathogens | Type I interferon regulates proteolysis by macrophages to prevent immunopathology following viral infection | 10.1371/journal.ppat.1010471 |
| Sophie M Poznanski, Ana Portillo, Manali Mukherjee, Anurag Bhalla, Kiho Son, Ali A Ashkar, Nader Khalidi, Parameswaran Nair | European Respritory Journal | Benralizumab’s anti-eosinophil efficacy may be decreased by impaired NK cell activity | https://doi.org/10.1183/13993003.02210-2021 |
| Housne Begum, Anand Swaminath, Yung Lee, Christine Fahim, Jonathan Bramson, Asghar Naqvi, Yaron Shargall, Christian Finley, Wael Hanna, John Agzarian | Translational Cancer Research | The histologic effects of neoadjuvant stereotactic body radiation therapy (SBRT) followed by pulmonary metastasectomy—rationale and protocol design for the Post SBRT Pulmonary Metastasectomy (PSPM) trial | https://doi.org/10.21037/tcr-22-232 |
| Richard D, Muthuirulan P, Aguiar J, Doxey AC, Banerjee A, Mossman K, Hirota J, Capellini TD | iScience | Intronic regulation of SARS-CoV-2 receptor (ACE2) expression mediated by immune signaling and oxidative stress pathways. | https://doi.org/10.1016/j.isci.2022.104614 |
| Semple SL, Au SKW, Jacob RA, Mossman KL, DeWitte-Orr SJ | Frontiers in Immunology | Discovery and Use of Long dsRNA Mediated RNA Interference to Stimulate Antiviral Protection in Interferon Competent Mammalian Cells | https://doi.org/10.3389/fimmu.2022.859749 |
| Rätze M, Koorman T, Sijnesael T, Bassey-Archibong BI, van de Ven R, EnserinkL, Visser D, Jaksani S, Bakker E, Richard F, Tutt A, Steele R, Pettitt S, Lord C, Fitzpatrick A, Isacke C, van Diest P, Desmedt C, Daniel JM, Derksen P | Oncogene | E-cadherin loss promotes invasive lobular breast cancer dormancy and CDK4/6 dependency through Id2-dependent inhibition of cell cycle progression. | https://doi.org/10.1038/s41388-022-02314-w |
| Hercules SM, Alnajar M, Chen C, Mladjenovic SM, Shipeolu BA, Perkovic O, Pond GR, Mbuagbaw L, Blenman KR, Daniel JM | BMJ Open | Triple-negative breast cancer prevalence in Africa: a systematic review and meta-analysis. | https://doi.org/10.1136/bmjopen-2021-055735 |
| Nader El-Sayes, Scott Walsh, Alyssa Vito, Amir Reihani, Kjetil Ask, Yonghong Wan, Karen Mossman | Molecular Theary Oncolytics | IFNAR blockade synergizes with oncolytic VSV to prevent virus-mediated PD-L1 expression and promote antitumor T cell activity | https://doi.org/10.1016/j.omto.2022.03.006 |
| Nader El-Sayes, Alyssa Vito, Omar Salem, Samuel Tekeste Workenhe, Yonghong Wan, Karen Mossman | International Journal of Molecular Sciences | A Combination of Chemotherapy and Oncolytic Virotherapy Sensitizes Colorectal Adenocarcinoma to Immune Checkpoint Inhibitors in a cDC1-Dependent Manner | https://doi.org/10.3390/ijms23031754 |
